Human and animal hormones are the messenger substances with specific regulating functions in the cells of their respective effector organs and, hence, control various physiologic processes. Hormones and their derivatives are used in hormonal therapy - a treatment that adds, blocks or removes hormones. This is beneficial, for example, for slowing down or stopping the growth of cancer cells that need hormones to grow. Hormones possess diverse chemical structures, belonging mainly to 3 classes: eicosanoids, steroids, and amino acid/protein derivatives.
Plant hormones are among the most important biochemicals affecting plant growth and crop yield under different conditions, including stress. Initial research into plant hormones identified five major classes: abscisic acid, auxin, cytokinins, ethylene and gibberellins.They are widely used in agriculture as specific treatment agents, for example, as weed killers or as rooting powders. They can also promote flowering and increase fruit size.
Our Hormone-related Focused Library, which is of 750 screening compounds in total, contains analogs of human and animal hormones/hormone-related agents (over 600 compounds), as well as plant hormones (around 40 compounds), selected from the Life Chemicals HTS Compound Collection by 2D fingerprints and Tanimoto similarity index of > 0.75. In addition, a separate set of 90 steroid-like compounds based on gonane scaffold is available as well.
The Library is aimed to facilitate hormone-related research, high throughput screening and drug discovery projects. Custom compound selection based on specific parameters can be performed on request.
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