The Life Chemicals collection of small organic molecules for high-throughput screening currently contains over 525,000 original drug-like compounds available in stock.
The HTS Collection as a whole is being constantly enlarged with structurally-diverse screening compounds that cover broad chemical space and possess optimal physicochemical properties for medicinal chemistry and drug discovery projects. To further develop and refine it, lead-oriented synthesis principles together with a scaffold-based approach for the design of new molecules are applied. The Collection genesis is depicted in Fig. 1.
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All the compounds are also available from our e-commerce website.
Custom compound selection based on specific parameters can be performed on request, with competitive pricing and the most convenient terms provided.
The shortest lead time and most customer-friendly terms are guaranteed.
The average physicochemical values and their relative distribution are reported in Fig. 2. All products undergo rigorous quality control to guarantee their purity of over 90 %, as confirmed with 400MHz NMR and/or LCMS.
Available for various research needs and areas are our novel and carefully designed Fragment Libraries, as well as Targeted and Focused Screening Libraries.
To make your drug discovery campaigns even more time- and cost-efficient, we are offering a constantly-growing collection of readily-available Pre-plated Screening Sets based on our best-selling Screening Compound Libraries.
Furthermore, our R & D team can carry out pioneering custom synthesis of individual compounds and compound libraries based on the Company’s proprietary scaffold database or parameters specified by the customer.
Significantly expanding our chemical domain is the Collection of Tangible Screening Compounds that includes over 2,500,000 virtual structures to be readily synthesized through in-house developed and validated synthetic procedures (feasibility of over 75 %).
Life Chemicals products and services are distinguished by their state-of-the-art standards and professionally recognized attractiveness to make them the most beneficial outsourcing opportunities for your R & D projects.
The Company’s strongest points are well presented under the Key Features and Benefits, including the full list of Early Drug Discovery Services available.
Our best R & D solutions are designed for you and around you!
Figure 1. General preparation workflow of the Life Chemicals HTS Compound Collection.
Figure 2. Physicochemical value distributions of the HTS Compound Collection.