Targeted and Focused Screening Libraries

Expertly applying various computational methods, such as molecular docking, pharmacophore modeling, similarity search, and machine learning used in modern drug design, Life Chemicals has successfully created one of the most diverse and balanced collections of targeted and focused libraries on the market.

The Targeted Screening Libraries comprise drug-like molecules with in silico predicted affinity to a target protein (or protein family), either by ligand-based or receptor-based approach, including established biological targets in various protein families: protein kinases, G-protein coupled receptors, ion channels, proteases, epigenetic and PPI-related targets, nuclear receptors, and many others.

Life Chemicals also provides Focused Compound Libraries that are built on molecular fingerprint similarity to reference sets of known ligands, inhibitors, and research compounds with demonstrated activity toward the target of interest (data extracted from research literature), while taking into account processed compound databases (ligand-based approach). These include focused libraries of small-molecule compounds with potential biological activity towards certain diseases (such as Anticancer, Antiviral or Antibacterial screening libraries, etc.), as well as those having their specific areas of applications (AgroChemical Libraries, CNS Targeted Library).

Shown below is the full list of targeted and focused sets available. All products included in these screening libraries and databases are available in stock, where any number of compounds can be selected or cherry-picked. Life Chemicals ready-made libraries can be supplemented by selections of a more specific character against a particular target under your investigation.