Expertly applying various computational methods, such as molecular docking, pharmacophore modeling, similarity search, and machine learning used in modern drug design, Life Chemicals has successfully created one of the most diverse and balanced collections of targeted and focused libraries on the market.
The Targeted Screening Libraries comprise drug-like molecules with in silico predicted affinity to a target protein (or protein family), either by ligand-based or receptor-based approach, including established biological targets in various protein families: protein kinases, G-protein coupled receptors, ion channels, proteases, epigenetic and PPI-related targets, nuclear receptors, and many others.
Life Chemicals also provides Focused Compound Libraries that are built on molecular fingerprint similarity to reference sets of known ligands, inhibitors, and research compounds with demonstrated activity toward the target of interest (data extracted from research literature), while taking into account processed compound databases (ligand-based approach). These include focused libraries of small-molecule compounds with potential biological activity towards certain diseases (such as Anticancer, Antiviral or Antibacterial screening libraries, etc.), as well as those having their specific areas of applications (AgroChemical Libraries, CNS Targeted Library).
Shown below is the full list of targeted and focused sets available. All products included in these screening libraries and databases are available in stock, where any number of compounds can be selected or cherry-picked. Life Chemicals ready-made libraries can be supplemented by selections of a more specific character against a particular target under your investigation.
Explore our Website for a detailed product description, or place an order online on our E-commerce website.
Download SD files with compound structures directly from our Downloads section. Please refer to the page How to work with Structured Data Files (SDF files) for details.
Custom compound selection based on specific parameters can be performed on request, with competitive pricing and the most convenient terms provided.

Furthermore, assay-ready Pre-plated Focused Libraries and Pre-plated Diversity Sets are available for your convenience.
Please, contact us at orders@lifechemicals.com for any additional information and price quotations.
- AgroChemical Screening Libraries
- Anti-hepatitis Screening Libraries
- Anti-HIV Screening Libraries
- Anti-inflammatory Screening Compound Library
- Antibacterial Screening Compound Libraries
- Anticancer Screening Compound Libraries
- Antimalarial Screening Libraries
- Antiprotozoal Screening Compound Library
- Antituberculosis Screening Compound Libraries
- Antiviral Screening Compound Libraries
- Aquaporin Screening Library
- ATPase Focused Libraries
- CNS Focused Screening Library
- Coronavirus Screening Libraries
- Cytochrome Inhibitor Library
- Degrader Building Blocks for Targeted Protein Degradation
- Deubiquitinase Screening Libraries
- DNA and RNA Polymerase Screening Libraries
- DNA-encoded (DEL) Reagents and Building Blocks
- Epigenetic Screening Libraries
- Glutamate Receptor Focused Library
- GPCR Screening Libraries
- Helicase Focused Library
- Hormone-related Focused Library
- Human Endogenous Retrovirus K (HERV-K) Inhibitor Library
- Immuno-oncology Screening Libraries
- Ion Channel Screening Libraries
- Kinase General Libraries
- Allosteric Kinase Screening Compound Library
- Kinase Focused Library by Similarity Search
- Kinase Screening Library (KSL)
- Kinase Targeted Libraries - Individual Screening Sets
- 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Targeted Library
- AKT Serine/threonine Kinase Targeted Library
- ALK Tyrosine Kinase Focused Library
- Aurora A Kinase Targeted Library
- Aurora B Kinase Targeted Library
- c-AMP Dependent Protein Kinase (PKA) Targeted Library
- c-Met (HGFR) Kinase Targeted Library
- Cyclin-dependent Kinase Screening Libraries
- Diacylglycerol Kinase (DGK) Targeted Library
- ERK5 (MAPK7) Kinase Targeted Library
- Fes/c-Fes Tyrosine Protein Kinase Targeted Library
- Fibroblast Growth Factor Receptor 1 Tyrosine Kinase Targeted Library
- Janus Kinase (JAK) Targeted Library
- p38 Mitogen-activated Protein (MAP) Kinase Focused Library
- Phosphatidylinositol 3-Kinase (PI3K) Targeted Library
- ROCK Kinase Targeted Library
- Vascular Endothelial Growth Factor Receptor Kinase 2 (VGFR-2) Focused Library
- Kinase Targeted Libraries by Docking
- Protein Kinase Diversity Set
- Tyrosine Kinase Screening Library
- Ligase Focused Screening Library
- Lysine-specific demethylase 4A (KDM4A) Targeted Library
- Metalloenzyme and Chelator Focused Libraries
- Nuclear Receptor Screening Libraries
- Pathway-based Screening Libraries
- Peptidomimetic Compound Library
- Phosphatase Screening Libraries
- Phosphodiesterase (PDE10) Targeted Library
- Protease Screening Libraries
- Protein-Protein Interactions (PPI) Screening Libraries
- RNA Focused and Targeted Libraries
- SH2 Domain Focused Library
- STING Targeted Library
- Transcription-related Screening Library
- Veterinary Focused Screening Library