Guarantee of high quality and purity of all compounds | Order and Supply

Life Chemicals has proven its leading position on the market, keeping high product and service standards with assured more than 90 % purity, as confirmed by LCMS and/or 400MHz NMR data. Electronic copies of NMR or LC-MS spectra are available upon request.

Life Chemicals provides additional customizable quality assurance services on request.

NMR Lab

The Laboratory provides compound characterization and structure determination by means of ¹H, ¹⁹F, ¹³C, ³¹P NMR spectroscopy together with advanced 2D NMR measurements (gradient COSY, NOESY, HMQC, HMBC, INADEQUATE, etc.) recorded on Varian® VNMRS 400 MHz.

The Laboratory’s daily output is more than 200 ¹H NMR spectra.

Chromatography Lab

The Laboratory is certified according to ISO/IEC 17025:2019 and provides analytical chromatography services with parameter variations on request (detection wavelength, mobile phase type, etc.). The Laboratory’s daily output is over 500 samples.

The preparative HPLC purification allows the isolation of highly pure compounds in milligram to multi-hundred gram quantities.

Physicochemical Research Lab

The Laboratory performs the following Quality Control services:

Advanced analytical and bioanalytical method development by computer-aided chromatographic techniques
HPLC-based high-throughput solubility measurements of fragments and other compounds with sample capacities up to 384 samples per day
Method development and scale-up for semi-preparative and preparative HPLC
Chiral chromatography and resolution of racemates with Advanced Laser Polarimeter (ALP) (PDR-Chiral) – on-line HPLC detector capable to distinguish enantiomeric form
Development of stereoselective methods for HPLC separation with ALP detection and specific rotation determination from a chromatogram
Enantiomeric Excess (ee) determination on a chiral column with ALP detection

Analytical Lab

The Laboratory is thoroughly equipped for comprehensive compound analysis, including:

Quality control of chemicals at each production stage: organic and inorganic reagents, laboratory solvents, synthesis intermediates, and final products
Qualitative and quantitative determination of functional groups and salt form of organic compounds
Water determination by Karl Fischer Titration (Titroline KF SCHOTT Instruments)
Optical activity measurement (POLAX-2L, ATAGO polarimeter)
Melting point verification (OptiMelt MPA100)
UV/Vis spectrophotometric analysis (SHIMADZU, 200-900 nm)