Early Drug Discovery Services

The entire toolbox of Life Chemicals products and services provides most efficient mechanisms to open up boundless horizons of drug discovery endeavor for its customers to test and implement their daring ideas.

Entering the very first stage of your search for an appropriate product candidate by scrutinizing our HTS libraries, you can take all advantages of stock and tangible structures, chemoinformatics, medicinal chemistry design, as well as any services presented below to get compounds completely ready for screening and hit follow-up:

MedChem Design and Synthesis

  • Most up-to-date MedChem know-how
  • Over 25-year experience in BigPharma research projects
  • More than 50 experienced synthetic chemists
  • All compounds are synthesized in-house with > 25,000 novel organic molecules added to our product catalog annually
  • Collaborative R&D, CRO services in terms of both fixed priced and FTE approaches.
  • 13,000 off-the-shelf Building Blocks in multigram quantities
  • Custom Synthesis of building blocks and intermediates
  • Lead-oriented scaffold-based screening libraries
  • In-house and customized library design
  • Hit-to-lead and lead optimization, SAR
  • Process optimization, route-scouting and scale-up
  • Scaffold hopping, introduction of conformational restrictions, bioisosteric replacement, peptidomimetics
  • 2,500,000 Tangible Screening Compounds to be readily synthesized through in-house developed and validated synthetic procedures
  • Customizable quality assurance services

HTS Compound Collection

Computational Chemistry Services

  • Computer-aided molecular design:
    • Virtual screening by docking
    • Pharmacophore, shape and similarity-based search
    • Machine learning, clustering
  • Physicochemical properties calculations
  • ADMET prediction
  • QSAR, diversity search
  • Molecular dynamics simulation
  • Structural bioinformatics

In Vitro ADMET Tests




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