Featured Products
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Pre-plated Diversity Sets
new
Our exclusive non-overlapping Pre-plated Diversity Sets containing 50,000 novel structurally diverse molecules were selected by dissimilarity search to provide a higher variety and broader chemical space coverage. They are an ideal starting kit for phenotypic and target-based HTS. Smaller subsets of 5,000, 10,000, 15,000, and 20,000 screening compounds are also available to meet your research needs.
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3D Compound Libraries for HTS
new
The 3D shape of a free ligand is a crucial feature for its molecular recognition by the desired biomolecule and affinity to the binding site. Explore our new proprietary collection of over 30,000 non-planar sp3-rich screening compounds with diverse and well-developed 3D shapes as remarkably attractive molecules for HTS in modern drug discovery.
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Transcription-related Screening Library
new
Many diseases, such as neurodegenerative disorders, diabetes, and cancer, are associated with the deregulation of transcriptional networks. To support the transcription-related drug discovery, we have designed a dedicated set of over 9,200 small-molecule screening compounds that are potential modulators of transcription-associated protein targets.
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Anti-inflammatory Screening Compound Library
updated
Over 2,900 drug-like screening compounds for a new anti-inflammatory screening and drug discovery research were selected with both ligand-based and receptor-based approaches. Explore our screening sets covering several stages of production and degradation of signaling intermediates (cytokines, phosphatidylinositol, prostaglandin, thromboxane, sphingosine-1-phosphate).
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Kinase Screening Library
new
Our Kinase Screening Library aims to provide initial hits for drug discovery projects related to kinases and other ATP-binding proteins. It was designed based on Markush structures and pharmacophore models of known kinase inhibitors. Exploring this Library of 3,000 drug-like screening compounds, you can find potential inhibitors targeting key protein kinases in cancer and inflammation, which were selected by 2D similarity search.
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Peptidomimetic Compound Library
new
Peptidomimetics are organic molecules that mimic the action of a natural peptide or protein, designed to overcome points of concern linked to natural peptides and to improve activity and selectivity. Among the whole variety of its products, Life Chemicals has prepared a proprietary Peptidomimetic Screening Library of over 5,800 α-helix and β-turn mimetics selected with a ligand-based approach.
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Fragment Library with Experimental Solubility
updated
An early assessment of solubility provides valuable information for better interpretation of screening results and the design of new molecules in drug discovery projects. Explore our 20,000 readily available fragments with confirmed solubility in PBS and DMSO! The Library is regularly updated with newly synthesized compounds, rigorously filtered by physicochemical and structural parameters.
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PI3K/Akt/mTOR Focused Library
new
The PI3K/AKT/mTOR signaling pathway plays a crucial role in a number of diseases, including ischemic brain injury, neurodegenerative disorders, and cancer. At Life Chemicals, we are pleased to introduce a novel PI3K/Akt/mTOR Focused Library of 4,400 drug-like screening compounds selected by a ligand-based approach for anti-cancer drug discovery projects.
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