In general, veterinary drugs are vitally important for maintaining the health and productivity of agricultural and companion animals. As a matter of fact, animal health drugs can be used for various purposes, such as therapeutic, prophylactic, growth promotion and others. Although there are many parallels between development of animal medicines and human drugs, there are also important differences. A modern veterinarian has a wide range of pharmaceuticals from which to choose in treatment and prevention of animal diseases: antimicrobial and anti-inflammatory agents, parasiticides, anesthetics and tranquilizers, and cancer chemotherapeutics. All are subject to governmental regulations, which vary by country.
Life Chemicals has designed a Veterinary Focused Library of 238 small-molecule screening compounds. It includes full structural analogs or structurally similar compounds to those from the reference set of FDA approved veterinary drugs, selected with a 2D similarity search against the Life Chemicals HTS Compound Collection.
The reference set (205 compounds) has been taken from the DrugBank (https://www.drugbank.ca). Similarity search has been done with the Fragment Based Fingerprints and Tanimoto index > 0.75. For each compound, the similarity information (similarity value and corresponding reference compound from the DrugBank) is indicated. This Veterinary Screening Compound Library is a product of choice for the area of animal science and veterinary medicine.
In addition to the above applications, a separate and highly important field is discovery and development of veterinary antiparasitic drugs. Available for your search are Antiprotozoal and Antimalarial Screening Libraries where structurally diverse screening compounds for HTS and HCS veterinary drug discovery can be found. Furthermore, Anti-inflammatory, Antiviral and Antibacterial Screening Libraries can be of interest for your projects.
Custom compound selection based on specific parameters can be performed on request, cherry-picking is available. Please, contact us at orders@lifechemicals.com for any details and quotations.
Fig. 1. Examples of known veterinary drugs from DrugBank
Fig 2. Some representative compounds from the Life Chemicals Veterinary Focused Library.