In general practice, veterinary drugs are vitally important for maintaining the health and productivity of agricultural and companion animals. As a vast arsenal of medicines, animal health drugs are used for various purposes, such as therapeutic, prophylactic, and growth promotion. Although there are many parallels between the development of animal medicines and human drugs, there are also significant differences. A modern veterinarian has a broad range of pharmaceuticals from which to choose in the treatment and prevention of animal diseases: antimicrobial and anti-inflammatory agents, parasiticides, anesthetics and tranquilizers, and cancer chemotherapeutics. All are subject to governmental regulations, which vary by country.
Life Chemicals has designed a Veterinary-focused Screening Library of 538 small-molecule screening compounds. It includes complete structural analogs or structurally similar compounds to those from the reference set of FDA-approved veterinary drugs, selected with a 2D similarity search against the Life Chemicals HTS Compound Collection.
The reference set (over 300 compounds) has been selected from the DrugBank and ChEMBL. Our similarity search has been done with the Fragment-based Fingerprints and Tanimoto index > 0.75. The similarity information (similarity value and corresponding reference compound) is indicated for each compound. This Veterinary Screening Compound Library is to become a remarkable practical tool for both animal science and veterinary medicine.
In addition to the above applications, a separate and critical field of interest is the discovery and development of veterinary antiparasitic drugs. Antiprotozoal and Antimalarial Screening Libraries are available for your search, where structurally diverse screening compounds for HTS and HCS veterinary drug discovery can be found.
Furthermore, Anti-inflammatory, Antiviral, and Antibacterial Screening Libraries can well be predicted to open up helpful resources for many versatile projects.
Please, contact us at orders@lifechemicals.com for any additional information and price quotations.
The compound selection can be customized based on your requirements, cherry picking is available.
Figure 1. Structures of representative compounds from each class of antimicrobials used as veterinary drugs [1]
![Figure 2. A series of processes involving veterinary drug residues in the human body [1].](img/library_descriptions/Veterinary%20Focused%20Screening%20Library/Veterinary_focused_screening_library_2.png "Figure 2. A series of processes involving veterinary drug residues in the human body")
Figure 2. A series of processes involving veterinary drug residues in the human body [1].
Representative screening compounds from the Veterinary Focused Screening Library:
References:
- Wang, B.; Xie, K.; Lee, K. Veterinary Drug Residues in Animal-Derived Foods: Sample Preparation and Analytical Methods. Foods 2021, 10, 555. https://doi.org/10.3390/foods10030555