Protein-Protein Interactions (PPI) Screening Libraries

Protein-protein interactions (PPIs) are involved in important biological processes in living organisms, and their regulation can be crucial for the treatment of numerous diseases [1]. In this context, PPIs are an attractive emerging class of molecular targets and are critically important in the progression of many disease states [1,2]. PPI inhibition with small molecules is a tremendously important diagnostic and therapeutic strategy that may lead to greatly protracted remissions and even curative therapies for a number of diseases [2].

Life Chemicals offers a proprietary collection of potential PPI modulators. PPI-focused screening compounds were selected by both ligand-based (2D fingerprint similarity search, decision tree method) and receptor-based (molecular docking, high-throughput virtual screening) approaches.

The compound selection can be customized based on your requirements, cherry picking is available.

Please, contact us at for any additional information and price quotations.


  1. Mabonga L, Kappo AP. Protein-protein interaction modulators: advances, successes and remaining challenges. Biophys Rev. 2019;11(4):559-581. 
  2. Macalino SJY, Basith S, Clavio NAB, Chang H, Kang S, Choi S. Evolution of In Silico Strategies for Protein-Protein Interaction Drug Discovery. Molecules. 2018;23(8):1963. 
This site uses cookies. Some of these cookies are essential, while others help us improve your experience by providing insights into how the site is being used. By using our website, you accept our conditions of use of cookies to track data and create content (including advertising) based on your interest. Accept