Phosphatase Screening Libraries

Protein phosphorylation is vital for normal cellular function, as it is a major control mechanism of a wide range of physiological processes. Phosphatases are enzymes that catalyze the dephosphorylation process. These enzymes replace a phosphate group in a substrate with a hydroxyl group from activation water. The action of phosphatases is directly opposite to that of phosphorylases and kinases. They play a significant role in signal transduction pathways and control a vast variety of cellular processes, including metabolism, gene transcription and translation, cell-cycle progression, cytoskeletal rearrangement, protein-protein interactions (PPI), protein stability, cell movement, and apoptosis.

At Life Chemicals, we have designed several proprietary Phosphatase-related Screening Libraries of drug-like screening compounds, carefully selected by computational chemistry methods to boost phosphatase-targeted drug discovery:

  • ligand-based drug design (2D fingerprint similarity search)
  • receptor-based drug design (molecular docking, high-throughput virtual screening, de novo protein reconstruction)

Please, contact us at for any additional information and price quotations.

The compound selection can be customized based on your requirements, cherry picking is available.

Visit our Website for a detailed product description, or place an order online on our E-commerce website.

Download SD files with compound structures directly from our Downloads section

You can also be interested in our related products:
This site uses cookies. Some of these cookies are essential, while others help us improve your experience by providing insights into how the site is being used. By using our website, you accept our conditions of use of cookies to track data and create content (including advertising) based on your interest. Accept