It is known that protein kinases are enzymes that catalyze phosphorylation, thus regulating the energy balance. Therefore, kinases are crucial in cell signaling, metabolism, protein regulation, as well as cellular transport, and many other cellular pathways. Overall, the US FDA approved 52 small-molecule protein kinase inhibitors by 2020. Over the past 15 years, protein kinases have become the pharmaceutical industry’s most important class of drug targets in the field of cancer.
The development of novel specific kinase inhibitors may lead to the discovery of potent anti-cancer drugs. In response to this market demand Life Chemicals has prepared a proprietary collection of drug-like screening compounds with potential kinase inhibitory activity to facilitate kinase-based drug discovery. The offered Screening Libraries were designed by a computer-aided approach, employing docking-based virtual screening for the kinase active site against the Life Chemicals HTS Compound Collection.
Compound cherry-picking within each screening library is available. Custom compound selection based on specific parameters can be performed, with the most convenient terms and competitive pricing provided.
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