New Release: SOS1 Inhibitor Screening Library

June 09, 2026

We are happy to introduce our SOS1 Inhibitor Screening Library, a focused set of 2,600 drug-like compounds designed to identify modulators of the SOS1-KRAS interaction within the RAS-MAPK signaling pathway.

By targeting SOS1, a key activator of RAS, these screening compounds support oncology research programs seeking alternative strategies to inhibit RAS-driven signaling in cancers, particularly pancreatic and lung malignancies.

Developed using structure-based virtual screening and refined with medicinal chemistry filters, the library offers:

  • Enriched chemical matter with predicted SOS1 binding
  • Reduced assay-interference risk
  • Chemically diverse and synthetically accessible compounds

The library is available for prompt delivery. 

Contact us at marketing@lifechemicals.com to get the list of compounds or additional details.

 

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