Latest Publication: “Two- and Three-Phase Self-assembly of Molecular Capsules”

February 16, 2023

We are happy to announce a new publication by our scientific team “Two- and Three-Phase Self-assembly of Molecular Capsules” (ChemistrySelect, 2022, DOI: 10.1002/slct.202200666).

Resorcinarenes are known to be versatile macrocyclic platforms for many covalent and supramolecular assemblies serving a variety of applications, such as ion-channel mimics, catalysis, and drug delivery. Life Chemicals offers highly effective custom synthesis of functionalized resorcin[4]- and [6]arene derivatives.

This article focuses on hydrogen-bonded dimers of self-complementary resorcin[4]arene tetraphosphates and tetramethylammonium and tropylium salts that form capsule-separated ion pairs in two- and three-phase systems. Efficient molecular encapsulation of the cations enables the separation of ion pairs, dissolution of insoluble components, and stabilization of the capsular complexes in a chloroform solution.

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See the whole list of Publications by Life Chemicals scientific team. For further reading, please, refer to our MedChem blog dedicated to Building Blocks and Custom synthesis.

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