Introducing Our Pre-plated Serine Protease Diversity Screening Set

We are excited to announce the launch of our latest Pre-plated Serine Protease Diversity Screening Set, comprising 1,920 drug-like compounds with predicted inhibitory activity against serine proteases. These small-molecule analogs of known serine protease inhibitors have been meticulously selected from our proprietary Serine Protease Screening Libraries, ensuring high structural diversity.

  Key Features:

• Exclusive Drug-like Molecules: novel screening compounds synthesized in-house, free from PAINS, reactive, toxic or unstable structures

• High Quality Standards: over 90 % purity confirmed by LCMS and/or NMR

• Comprehensive Support: cheminformatics assistance, hit re-supply  and product scale-up

• Rapid Worldwide Delivery: fast and reliable shipping to ensure seamless project timelines

• Customer-oriented Solutions: flexible formatting options to match your project needs and always competitive pricing

  Formatting Options:

• 10 mM solutions in DMSO

• Volumes available: 10 µL, 25 µL, 50 µL, 100 µL

• 384-well microplates (Greiner bio-one ref: 781280 or 784201)

• Standard layout: 320 compounds per plate; columns 1-2 and 23-24 left empty

 In addition to this ready-to-use set, we offer customizable Protease Screening Libraries, allowing you to cherry-pick compounds and design tailored sets targeting specific proteases. Our selection process employs both ligand-based approaches, such as computational chemistry and 2D fingerprint similarity searches, and receptor-based methods, including high-throughput virtual screening and flexible and covalent docking.

 Contact us at marketing@lifechemicals.com to discuss your needs to advance protease drug discovery research. Also, explore our specialized screening compounds to accelerate a wider range of your projects.