Bioactive Compounds and Materials Based on Functionalized 1,3,4-Oxadiazoles
A number of the 1,3,4-oxadiazoles have shown a very broad spectrum of biological activity: anti-cancer activity, inhibitors of various enzymes, herbicides, antifungal activity.
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Functionalized 1,3,4-Thiadiazoles for Various Applications in Drug Discovery, Agrochemistry, and Materials Technology
Derivatives of 1,3,4-thiadiazoles possess a wide spectrum of biological activity and have found numerous applications in medicine, agriculture, and materials technology.
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Substituted Azetidines in Drug Discovery
Azetidines are an important class of aza-heterocyclic compounds with remarkable biological activities. Presently ca. 60 approved and over 30 experimental drugs bear the moiety of azetidine-2-one.
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Explore Our Hetaryl-tethered Natural Derivatives of Chromone and Coumarin
Natural products bearing chromone and coumarin substructures possess a broad spectrum of biological activities by altering the catalytic function of numerous enzymatic reactions. Life Chemicals offer hetaryl-tethered natural derivatives of chromone and coumarin for organic synthesis and medicinal chemistry projects.
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Functionalized (-)-Cytisine Derivatives for Medicinal Chemistry and Organic Synthesis
Naturally occurring alkaloid ()-cytisine is an efficient acetylcholine agonist possessing a strong affinity to nicotinic acetylcholine receptors (nAChRs). Its various chemical modifications were applied to obtain novel bicyclic compounds for rational drug discovery. Life Chemicals offers derivatives of ()-cytisine including those involving chromone, coumarin, and other heterocyclic substructures.
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