Building Blocks

Boost your Medicinal Chemistry Research with C-substituted Piperidines

Piperidine-based building blocks have found extensive application in medicinal chemistry. The piperidine substructure is also present in a variety of biologically active natural products, synthetic pharmaceuticals, and agrochemicals. Life Chemicals offers a selection of functionalized C-substituted piperidines.

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11 march 2021, 17:42    Oleg Lukin Building Blocks

Boost your Research with our Original Cyclopropanes

Small and lipophilic cyclopropane rings are finding increasingly sophisticated use in pharmaceuticals. We offer a proprietary collection of subsituted cyclopropane derivatives for intorduction of conformational constraints into small molecules and peptide ligands in drug discovery efforts.

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15 february 2021, 14:45    Oleg Lukin Building Blocks

We Prepared a Set of Functionalized 1,3-Thiazoles to Power Up Your Research

The structural unit of substituted 1,3-thiazole is ubiquitous in natural products and synthetic materials, while thiazole moiety is a privileged scaffold in drug discovery.

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18 january 2021, 15:55    Oleg Lukin Building Blocks

Explore Our Novel Cyclobutane Derivatives

Сyclobutanes are heavily exploited in organic synthesis as subunits for natural product preparation, ring-opening, and ring-contraction reactions. In medicinal chemistry, the introduction of a cyclobutane fragment is often used to achieve a conformational restriction.

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14 december 2020, 17:28    Oleg Lukin Building Blocks

C-Substituted Azepanes for Novel Organic Synthesis and Drug Discovery Research

Azepane derivatives attract considerable attention in organic synthesis and drug discovery. There are several naturally occurring azepane derivatives possessing a number of biological activities.

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12 november 2020, 12:19    Oleg Lukin Building Blocks
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