Functionalized Pyridines as Valuable Building Blocks in Organic Synthesis and Medicinal Chemistry
The structural unit of substituted pyridine occurs in numerous important compounds including natural products such as vitamins, coenzymes, and alkaloids as well as synthetic pharmaceuticals and agrochemicals.
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Conformationally Restricted Diamines in Medicinal Chemistry and Drug Discovery
Conformationally restricted diamines (CRDAs) are especially attractive scaffolds for drug discovery because they offer the potential of the wide variability in the relative spatial arrangement of functional groups.
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1,2,4-Oxadiazole Derivatives to Power Up Your Research
1,2,4-oxadiazole moiety is used in peptidomimetics, a stable isostere of ester and amide functionalities. The 1,2,4-oxadiazoles are promising building blocks in organic synthesis, drug discovery and materials science.
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Functionalized Isoxazoles to Augment Your Building Block Collection
Isoxazole derivatives are versatile synthetic building blocks due to their dormant functionalities. The substituted isoxazole unit is present in several natural products, synthetic drugs, and other biologically active compounds.
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Expand your building block collection with our C-Substituted Morpholines
Morpholines and their homologs are highly represented among small molecules that are biologically and therapeutically relevant, including many natural products. Morpholine scaffolds have also been widely utilized in the agrochemical industry and as chiral auxiliaries in asymmetric synthesis.
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