Building Blocks

Derivatives of 1,2,4-triazole have been actively used for the preparation of numerous biologically active substances and functional materials. At Life Chemicals, we have developed a proprietary collection of functionalized 1,2,4-triazoles that are promising reagents for the synthesis of new biologically potent or functional compounds.

A number of the 1,3,4-oxadiazoles have shown a very broad spectrum of biological activity: anti-cancer activity, inhibitors of various enzymes, herbicides, antifungal activity.

Derivatives of 1,3,4-thiadiazoles possess a wide spectrum of biological activity and have found numerous applications in medicine, agriculture, and materials technology.

Azetidines are an important class of aza-heterocyclic compounds with remarkable biological activities. Presently ca. 60 approved and over 30 experimental drugs bear the moiety of azetidine-2-one.

Natural products bearing chromone and coumarin substructures possess a broad spectrum of biological activities by altering the catalytic function of numerous enzymatic reactions. Life Chemicals offer hetaryl-tethered natural derivatives of chromone and coumarin for organic synthesis and medicinal chemistry projects.