Building Blocks

Expand Your Building Block Collection with Our Functionalized 1,3-Oxazoles

A large number of substituted oxazole-containing natural products have been isolated, mostly from marine microorganisms. Many of these natural products are structurally complex and of considerable biological interest.

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30 june 2020, 17:15    Oleg Lukin Building Blocks

Explore Our Functionalized 1,2,3-Triazoles for Diverse Applications

1,2,3-Triazoles are important structural motifs in diverse research fields, ranging from medicinal chemistry and agriculture to materials science. These heterocycles have proved very valuable as isostere of the amide group in bioactive molecules on account of their remarkable metabolic stability.

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02 june 2020, 18:34    Oleg Lukin Building Blocks

Novel Conformationally Restricted Amino Acids for Peptidomimetic Drug Design

Conformationally restricted amino acids and peptides in which conformational freedom is substantially reduced by the presence of small rings have assumed a prominent role in drug design and development. They are used in the peptidomimetic drug design as surrogates of proline.

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18 february 2020, 17:18    Oleg Lukin Building Blocks

C-Substituted Pyrrolidines from Life Chemicals Inspiring Your Drug Discovery Endeavour!

Pyrrolidines are an important class of heterocycles found in numerous natural products, bioactive molecules and organocatalysts. In view of this, Life Chemicals designed its original pyrrolidine-based building blocks to inspire organic synthesis and medicinal chemistry projects.

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07 january 2020, 18:59    Oleg Lukin Building Blocks

Take a Closer Look at Our Original Functionalized Pyridazines!

The structural unit of substituted pyridazine is present in many biologically active compounds and a lot of research is now focused on the synthesis of novel pyridazine-based building blocks and combinatorial libraries.

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10 december 2019, 12:05    Oleg Lukin Building Blocks