Building Blocks

The structural unit of substituted pyridazine is present in many biologically active compounds and a lot of research is now focused on the synthesis of novel pyridazine-based building blocks and combinatorial libraries.

Pyrazine substructure is present in many biologically and technologically relevant compounds. Substituted pyrazines are widely used as pharmaceuticals, while pyrazine-based polymers and other light-responsive materials are of high interest for technological applications.

Pyrimidine derivatives are by far the most important compounds in living organisms, including subunits of RNA, DNA and many natural antibiotics. Despite a large number of marketed pyrimidine-based drugs and agrochemicals, functionalized pyrimidines are still heavily employed as building blocks in drug discovery programs.

Pyrazole fragment is found in many low-molecular weight compounds possessing a wide range of biological activities and materials science related properties. Life Chemicals offers a set of novel functionalized pyrazoles that are perfectly suited for the use in drug discovery and organic synthesis.

Compounds bearing a carbonyl group conjugated with a carbon-carbon double bond are important subunits of biologically active species and monomers for functional polymers. Recent interest in these compounds is associated with the design of covalent inhibitors, which represent promising drugs for the treatment of thrombosis and various cancers. Life chemicals offers structurally diverse compounds, bearing carbon-carbon double bonds activated by either carbonyl or sulfo-groups.