Building Blocks

1,2,4-Oxadiazole Derivatives to Power Up Your Research

1,2,4-oxadiazole moiety is used in peptidomimetics, a stable isostere of ester and amide functionalities. The 1,2,4-oxadiazoles are promising building blocks in organic synthesis, drug discovery and materials science.

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06 july 2021, 17:54    Oleg Lukin Building Blocks

Functionalized Isoxazoles to Augment Your Building Block Collection

Isoxazole derivatives are versatile synthetic building blocks due to their dormant functionalities. The substituted isoxazole unit is present in several natural products, synthetic drugs, and other biologically active compounds.

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08 june 2021, 13:58    Oleg Lukin Building Blocks

Expand your building block collection with our C-Substituted Morpholines

Morpholines and their homologs are highly represented among small molecules that are biologically and therapeutically relevant, including many natural products. Morpholine scaffolds have also been widely utilized in the agrochemical industry and as chiral auxiliaries in asymmetric synthesis.

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26 april 2021, 15:40    Oleg Lukin Building Blocks

Boost your Medicinal Chemistry Research with C-substituted Piperidines

Piperidine-based building blocks have found extensive application in medicinal chemistry. The piperidine substructure is also present in a variety of biologically active natural products, synthetic pharmaceuticals, and agrochemicals. Life Chemicals offers a selection of functionalized C-substituted piperidines.

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11 march 2021, 17:42    Oleg Lukin Building Blocks

Boost your Research with our Original Cyclopropanes

Small and lipophilic cyclopropane rings are finding increasingly sophisticated use in pharmaceuticals. We offer a proprietary collection of subsituted cyclopropane derivatives for intorduction of conformational constraints into small molecules and peptide ligands in drug discovery efforts.

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15 february 2021, 14:45    Oleg Lukin Building Blocks
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