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Expand Your Building Block Collection with Our Functionalized 1,3-Oxazoles

A large number of substituted oxazole-containing natural products have been isolated, mostly from marine microorganisms. Many of these natural products are structurally complex and of considerable biological interest.

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30 june 2020, 17:15    Oleg Lukin Building Blocks

Custom Synthesis of Versatile Chalcone-4’-sulfonyl Derivatives

Functionalized benzylidene acetophenones (chalcones) are attractive building blocks for introducing the conjugated motif of a carbonyl group and a carbon-carbon double bond into potential drugs, such as covalent inhibitors or monomers for synthetic polymers. The substructure of chalcone is found in many drugs and biologically active compounds.

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17 june 2020, 14:56    Alexander Shivanyuk Custom synthesis

Explore Our Functionalized 1,2,3-Triazoles for Diverse Applications

1,2,3-Triazoles are important structural motifs in diverse research fields, ranging from medicinal chemistry and agriculture to materials science. These heterocycles have proved very valuable as isostere of the amide group in bioactive molecules on account of their remarkable metabolic stability.

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02 june 2020, 18:34    Oleg Lukin Building Blocks

Cysteine-related Libraries for Anti-coronavirus Research

One of the best-characterized drug targets among coronaviruses, including current SARS-CoV2 causing coronavirus disease 2019 (COVID-19), is the main protease (3CLpro, or Mpro). Our efforts to help fighting the COVID-19 resulted in a number of screening compound libraries, including those specifically focused on cysteine.

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09 may 2020, 10:03    Andrew Golub Computational Chemistry

World Malaria Day 2020: on the Lookout for Advanced Antimalarial Drugs

Every year on April 25th the World Health Organization highlights the importance and urgency of the global malaria problem by marking the World Malaria Day. To join the worldwide efforts to curb malaria and to support all domains of antimalarial research, Life Chemicals provides a selection of malaria-relevant compounds in its focused screening libraries.

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24 april 2020, 16:55    Svitlana Kondovych Computational Chemistry