Functionalized Isoxazoles to Augment Your Building Block Collection

Isoxazole derivatives are versatile synthetic building blocks due to their dormant functionalities. The substituted isoxazole unit is present in several natural products, synthetic drugs, and other biologically active compounds.

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08 june 2021, 13:58    Oleg Lukin Building Blocks

Metal Chelation in Enzyme Active Sites for Drug Discovery

Metalloenzyme inhibitors form one of the most promising medication classes used to treat various pathologies, including cancer, viral and bacterial infections, neurodegenerative and other diseases. Life Chemicals is offering several screening compound libraries of small organic molecules that serve as potential chelating ligands.

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12 may 2021, 15:11    Svitlana Kondovych Computational Chemistry

Expand your building block collection with our C-Substituted Morpholines

Morpholines and their homologs are highly represented among small molecules that are biologically and therapeutically relevant, including many natural products. Morpholine scaffolds have also been widely utilized in the agrochemical industry and as chiral auxiliaries in asymmetric synthesis.

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26 april 2021, 15:40    Oleg Lukin Building Blocks

Key Events in Epigenetic Drug Discovery

Epigenetics is an exciting research field with vast clinical implications. At Life Chemicals, we have recently updated and re-designed our Epigenetic Targeted and Focused Libraries with an emphasis on most-promising epigenetic-related targets and ligands in response to epigenetic drug discovery trends.

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12 april 2021, 17:21    Andrew Golub Computational Chemistry

Boost your Medicinal Chemistry Research with C-substituted Piperidines

Piperidine-based building blocks have found extensive application in medicinal chemistry. The piperidine substructure is also present in a variety of biologically active natural products, synthetic pharmaceuticals, and agrochemicals. Life Chemicals offers a selection of functionalized C-substituted piperidines.

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11 march 2021, 17:42    Oleg Lukin Building Blocks
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